A very important poem from this period San Leupphasun (Lao: ສານລຶພສູນ) discusses relations involving Laos and Thailand in the veiled way, utilizing the Nāga and also the Garuḍa to characterize the Lao plus the Thai, respectively.[56] The Nāga is integrated thoroughly into Lao iconography, and options prominently in Lao culture through the entire duration in the place, not just in Vientiane.
enzyme can bind but only one divalent cation during the Lively site. For your binuclear steel Middle, the activation in the amide bond as well as activation of the solvent water is usually dispersed individually involving the two metallic ions. On the other hand, from the mononuclear metallic center, equally capabilities needs to be borne by a single divalent cation. These success emphasize the numerous range for that evolution of perform within the amidohydrolase superfamily.
The constructions from the compounds tested as substrates for NagA are introduced in Plan 6. The substitution of sulfur for oxygen may be used at the side of hard and gentle metals to probe the potential for metallic-ligand conversation during the activation of electrophilic reactions (24, 25).
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Residues Q59 and N61 had been mutated jointly to your set of histidine residues to generate an HxH motif which is analogous to that present in NagA from B. subtilis
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